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DOH Pharmacology Nursing Practice Questions

What this topic covers

High-alert medicines, antidotes, side effects, the rights of medication administration and dosage calculations.

Free DOH pharmacology nursing questions

1. A patient with a deep vein thrombosis is started on warfarin while continuing enoxaparin. The patient asks why both are needed. What is the best explanation?
  1. The two drugs must always be taken together for life
  2. Warfarin takes several days to reach its full anticoagulant effect
  3. Enoxaparin increases the absorption of warfarin
  4. Enoxaparin prevents the side effects of warfarin
Show answer and rationale

Answer: B. Warfarin takes several days to reach its full anticoagulant effect

Warfarin's effect depends on depletion of existing clotting factors, which takes several days, so a parenteral anticoagulant is overlapped until the INR is therapeutic.

Reference: Standard nursing pharmacology – warfarin

2. A patient taking carbamazepine reports a sore throat, fever and mouth ulcers. What should the nurse do?
  1. Advise the patient to double the next dose
  2. Report it promptly because it may indicate a blood disorder such as agranulocytosis
  3. Reassure the patient that these are expected side effects
  4. Advise throat lozenges and continue the drug
Show answer and rationale

Answer: B. Report it promptly because it may indicate a blood disorder such as agranulocytosis

Carbamazepine can cause bone marrow suppression; signs of infection need an urgent full blood count and review.

Reference: Standard nursing pharmacology – carbamazepine

3. A child weighing 20 kg is prescribed paracetamol 15 mg/kg orally. What dose should the nurse give?
  1. 300 mg
  2. 450 mg
  3. 200 mg
  4. 150 mg
Show answer and rationale

Answer: A. 300 mg

Dose = 15 mg/kg × 20 kg = 300 mg.

Reference: Standard dosage calculation – weight-based dosing

4. A patient refuses the prescribed morning dose of an antihypertensive. What is the most appropriate nursing action?
  1. Tell the patient the prescriber insists the tablet must be taken
  2. Explore the reason for refusal, provide information, and document and report the refusal if the patient still declines
  3. Hide the tablet in the patient's breakfast
  4. Leave the tablet on the bedside table for later
Show answer and rationale

Answer: B. Explore the reason for refusal, provide information, and document and report the refusal if the patient still declines

A competent patient has the right to refuse; the nurse explores concerns, educates, respects the decision, documents and informs the prescriber. Covert administration and leaving medicines unattended are unsafe.

Reference: Potter & Perry Fundamentals – medication administration

5. A paediatric infusion is prescribed at 50 mL/h using a microdrip giving set (60 drops/mL). What is the drip rate?
  1. 50 drops/min
  2. 12 drops/min
  3. 100 drops/min
  4. 25 drops/min
Show answer and rationale

Answer: A. 50 drops/min

(50 mL × 60 drops/mL) ÷ 60 min = 50 drops/min. With a 60 drops/mL set, drops per minute equal mL per hour.

Reference: Standard dosage calculation – gravity drip rates

Questions are written with AI assistance. About 10% (150+) have been reviewed by a licensed nurse so far, and more are reviewed every month. Practice questions are for study only and may contain mistakes; verify with official study guides from your destination country. Report a question

Study tip

Practise calculations without a calculator shortcut and double-check units; one decimal slip is a wrong answer.

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